the 4s if setup right will make more watts with less amps. watts is amps times volts. it all depends if you need the power or not. it involves re propping to make work right, usually a size or two smaller like 8" or 9" depending on the load it carries
faster spinning props gives more vibrations
no question 4s is better all around. More power, more efficient, higher prop speed will show much less rolling shutter if none at all, better in wind.....